{"id":1938,"date":"2017-05-14T16:08:39","date_gmt":"2017-05-14T15:08:39","guid":{"rendered":"http:\/\/slanedeti.sk\/cms\/?p=1938"},"modified":"2017-09-03T12:53:12","modified_gmt":"2017-09-03T11:53:12","slug":"novinky-z-vyskumu-cystickej-fibrozy-na-eccmid-2017","status":"publish","type":"post","link":"https:\/\/slanedeti.sk\/cms\/novinky-z-vyskumu-cystickej-fibrozy-na-eccmid-2017\/1938","title":{"rendered":"Novinky z v\u00fdskumu cystickej fibr\u00f3zy na ECCMID 2017"},"content":{"rendered":"

Vo Viedni sa koncom apr\u00edla konala v\u00fdznamn\u00e1 infektologick\u00e1 konferencia European Congress of Clinical Microbiology and Infectious Disesases (ECCMID). Konferencia mala \u0161irok\u00fd z\u00e1ber, reflektuj\u00faci s\u00fa\u010dasn\u00e9 t\u00e9my klinickej mikrobiol\u00f3gie ako s\u00fa napr. antibiotick\u00e1 rezistencia, \u0161\u00edrenie sa p\u00f4vodne exotick\u00fdch ochoren\u00ed (napr.zika, z\u00e1padon\u00edlska hor\u00fa\u010dka) do nov\u00fdch kraj\u00edn, antiinfek\u010dn\u00e1 lie\u010dba, vakcin\u00e1cia a pod. Viacero predn\u00e1\u0161ok a posterov sa tie\u017e venovalo problematike cystickej fibr\u00f3zy (CF). Z tohto poh\u013eadu \u00a0s\u00fa zauj\u00edmav\u00e9 aj \u010fal\u0161ie pr\u00edspevky, ktor\u00e9 s\u00edce neprezentovali priamo CF, ale patog\u00e9ny ktor\u00e9 s\u00fa popri in\u00fdch ochoreniach v\u00fdznamn\u00e9 aj pri CF (napr. <\/span>Pseudomonas aeruginosa<\/span><\/i>). V\u00e4\u010d\u0161ina obsahu je vo\u013ene pr\u00edstupn\u00e1 na adrese <\/span>http:\/\/www.eccmidlive.org<\/span><\/a> .<\/span><\/p>\n

Infekcie prin\u00e1\u0161aj\u00fa pacientom s CF mno\u017estvo probl\u00e9mov a popri pokroku v medic\u00edne sa sna\u017eia nezaost\u00e1va\u0165 ani bakt\u00e9rie. V poslednom obdob\u00ed bola u CF pacientov op\u00edsan\u00e1 koloniz\u00e1cia nov\u00fdmi druhmi bakt\u00e9ri\u00ed. S\u00favis\u00ed to aj s pokrokmi v diagnostike (PCR, DNA sekvenovanie), \u010das\u0165 pacientov bola \u201cnov\u00fdmi\u201c bakt\u00e9riami kolonizovan\u00e1 aj v minulosti, ale klasick\u00e9 mikrobiologick\u00e9 met\u00f3dy to neboli schopn\u00e9 zachyti\u0165. Na druhej strane zmeny ako zvy\u0161ovanie veku do\u017eitia, znamenaj\u00fa aj zmeny v koloniz\u00e1cii p\u013e\u00fac pacientov, viac druhov bakt\u00e9rii, antibiotick\u00fa<\/span> multirezistenciu a desa\u0165ro\u010dia trvaj\u00faci boj s chronick\u00fdmi infekciami. \u0160\u00edreniu patog\u00e9nov m\u00f4\u017eu napom\u00e1ha\u0165 aj nemedic\u00ednske faktory ako v\u00e4\u010d\u0161ia roz\u0161\u00edrenos\u0165 cestovania, zmeny kl\u00edmy.<\/span><\/p>\n

Ni\u017e\u0161ie uv\u00e1dzame inform\u00e1cie z niektor\u00fdch zauj\u00edmav\u00fdch prezentovan\u00fdch \u0161t\u00fadii.<\/span><\/p>\n

Celkov\u00fd poh\u013ead na mikrobiol\u00f3giu pri CF priniesla v predn\u00e1\u0161ke Barbara Kahl z Univerzitnej nemocnice v M\u00fcnsteri. Postupne sa zni\u017euje podiel pacientov so <\/span>Pseudomonas aeruginosa<\/span><\/i>, \u010do autorka pripisuje najm\u00e4 opatreniam na zamedzenie \u0161\u00edrenia tejto infekcie. Ni\u017e\u0161ie uveden\u00fd graf m\u00f4\u017ee by\u0165 v\u0161ak \u010diasto\u010dne skres\u013euj\u00faci, ke\u010f\u017ee multirezistentn\u00e1 pseudomon\u00e1da (MDR-PA) je od r. 2003 uveden\u00e1 samostatne. Na druhej strane sa zvy\u0161uje v\u00fdznam chronick\u00fdch stafylokokov\u00fdch infekci\u00ed, vr\u00e1tane MRSA.<\/span><\/p>\n

\"prevalence\"<\/p>\n

 <\/p>\n

Prevalencia bakt\u00e9ri\u00ed u CF pacientov, \u00fadaje z USA<\/span><\/em><\/p>\n

Staphylococcus <\/span><\/i>aureus<\/span><\/i> kolonizuj\u00faci pacientov \u010dasto vytv\u00e1ra aj u jedn\u00e9ho pacienta viacero klonov \u2013 tzv. Small Colony Variants (SCV), \u010do je mechanizmus prisp\u00f4sobenia sa bakt\u00e9rie. Jednotliv\u00e9 klony m\u00f4\u017eu by\u0165 indukovan\u00e9 \u0161pecifick\u00fdmi antibiotikami. SCV sa \u010dastej\u0161ie vyskytuj\u00fa u star\u0161\u00edch pacientov. SCV s\u00fa \u010dast\u00e9 pri <\/span>S. aureus<\/span><\/i>, ale vyskytuj\u00fa sa aj u in\u00fdch bakt\u00e9ri\u00ed (vr\u00e1tane <\/span>P. aeruginosa<\/span><\/i>). K menej \u010dast\u00fdm bakt\u00e9ri\u00e1m pri CF patr\u00ed <\/span>Stenotrophomonas maltophilia, <\/span><\/i>zatia\u013e nie je zrejm\u00e9, ak\u00fd m\u00e1 t\u00e1to bakt\u00e9ria klinick\u00fd v\u00fdznam, teda \u010di jej v\u00fdskyt vedie k zhor\u0161eniu zdravotn\u00e9ho stavu. Podobne je to pri <\/span>Achromobacter xylosoxidans<\/span><\/i>, ktorej v\u00fdskyt sa v poslednom obdob\u00ed u CF pacientov zvy\u0161uje, aj ke\u010f v tomto pr\u00edpade sa hromadia d\u00f4kazy o jej nepriaznivom vplyve na klinick\u00fd stav. Autorka tie\u017e zd\u00f4raznila, \u017ee diagnostick\u00e1 kultiv\u00e1cia CF patog\u00e9nov je \u0161pecifick\u00e1, vy\u017eaduje si viac druhov kultiva\u010dn\u00fdch p\u00f4d, \u0161peci\u00e1lne postupy, \u010do m\u00e1 zaru\u010di\u0165, aby nebola prehliadnut\u00e1 \u017eiadna bakt\u00e9ria, ktor\u00e1 kolonizovala pacienta.<\/span><\/p>\n

Timothy J. Kidd z austr\u00e1lskej University of Queensland prezentoval niektor\u00e9 zauj\u00edmav\u00e9 zistenia. Napr\u00edklad spojitos\u0165 infekci\u00ed so zmenou kl\u00edmy. V rokoch s vy\u0161\u0161\u00edm \u00fahrnom zr\u00e1\u017eok sa v Brisbane zv\u00fd\u0161il \u00a0u CF pacientov po\u010det infekci\u00ed bakt\u00e9riou <\/span>Burkholderia cepacia<\/span><\/i>.<\/span><\/p>\n

T\u00edm vedcov z Christian-Albrechts Universit\u00e4t v Kieli a Lademannbogen Medical Center v Hamburgu \u0161tudoval koloniz\u00e1ciu CF pacientov anaer\u00f3bnymi bakt\u00e9riami (bakt\u00e9rie schopn\u00e9 \u017ei\u0165 v prostred\u00ed bez kysl\u00edka). Anaer\u00f3bne bakt\u00e9rie zistili u 77% pacientov. Naj\u010datej\u0161ie rody boli <\/span>Prevotella<\/span><\/i>, <\/span>Veillonella<\/span><\/i>, <\/span>Fusobacterium<\/span><\/i>, \u00a0<\/span>Actinomyces<\/span><\/i>. \u010ealej pou\u017eili 16s rRNA sekvenovanie na ur\u010denie druhov bakt\u00e9ri\u00ed. Naj\u010dastej\u0161\u00edm druhom bol <\/span>Prevotella melaninogenica<\/span><\/i>, s odstupom menej zast\u00fapen\u00e9 boli <\/span>Prevotella salivae<\/span><\/i>, <\/span>Prevotella denticola<\/span><\/i>, <\/span>Prevotella histicola<\/span><\/i>, <\/span>Veillonella<\/span><\/i> parvula<\/span><\/i>.<\/span><\/p>\n

Britsk\u00e1 farmaceutick\u00e1 spolo\u010dnos\u0165 NovaBiotics prezentovala v\u00fdskum, pod\u013ea ktor\u00e9ho m\u00e1 cysteam\u00edn podporn\u00fd \u00fa\u010dinok pri lie\u010dbe p\u013e\u00facnych exacerb\u00e1ci\u00ed CF t\u00fdm, \u017ee zvy\u0161uje \u00fa\u010dinnos\u0165 viacer\u00fdch druhov antibiot\u00edk (aminoglykozidov, fluorochinol\u00f3nov, makrolidov). Tento v\u00fdskum je v skor\u00fdch \u0161t\u00e1di\u00e1ch, uskuto\u010d\u0148oval sa na bunkov\u00fdch kult\u00farach.<\/p>\n

V poslednom obdob\u00ed sa u CF pacientov pozoroval zv\u00fd\u0161en\u00fd v\u00fdskyt mykobakt\u00e9ri\u00ed nesp\u00f4sobuj\u00facich tuberkul\u00f3zu (non-tuberculous mycobacteria, NTM), najm\u00e4 druhov <\/span>Mycobacterium abscessus<\/span><\/i> a <\/span>Mycobacterium avium <\/span><\/i>complex. V\u00fdskum v tejto oblasti prezentoval t\u00edm z Hospital Universitario de la Princessa z Madridu. V\u00fdskum prebiehal na vzork\u00e1ch z pediatrick\u00e9ho oddelenia, pri\u010dom NTM sa vyskytli pribli\u017ene u 10 % pacientov, o nie\u010do \u010dastej\u0161ie u chlapcov ako u diev\u010dat.<\/span><\/p>\n

\u0160tudenti z University College Dublin prezentovali aplik\u00e1ciu My Bugs pre <\/span>Android<\/span><\/a> a iOS, ktorej pou\u017e\u00edvanie testovali spolu s 50 CF pacientmi. Aplik\u00e1cia umo\u017e\u0148uje pacientovi vies\u0165 si z\u00e1znamy o mikrobiologick\u00fdch kultiva\u010dn\u00fdch vy\u0161etreniach, predpisoch a u\u017e\u00edvan\u00ed antibiot\u00edk, mo\u017enos\u0165 zdiela\u0165 tieto inform\u00e1cie s lek\u00e1rom, \u010do m\u00e1 sprehladni\u0165 lie\u010dbu. Pod\u013ea autorov je odozva na aplik\u00e1ciu pozit\u00edvna a upgrady bud\u00fa obsahova\u0165 inform\u00e1cie o antibiotik\u00e1ch a rezistencii.<\/span><\/p>\n

V Gr\u00e9cku bola hodnoten\u00e1 \u00farove\u0148 o\u010dkovania CF pacientov vzh\u013eadom na n\u00e1rodn\u00fa o\u010dkovaciu sch\u00e9mu. Opodstatnenie pre tento v\u00fdskum vypl\u00fdva z toho, \u017ee ak\u00fatne zdravotn\u00e9 komplik\u00e1cie s\u00fa \u010dastou kontraindik\u00e1ciou o\u010dkovania, n\u00e1sledkom \u010doho sa odpor\u00fa\u010dan\u00e9 o\u010dkovanie \u010dasto od\u010fa\u013euje a rovnako vy\u0161\u0161ie riziko CF pacientov pri infekci\u00e1ch, najm\u00e4 d\u00fdchac\u00edch ciest (o\u010dkovanie m\u00e1 pre nich e\u0161te vy\u0161\u0161ie benefity). Odborn\u00edci z Hel\u00e9nskeho centra pre kontrolu a prevenciu ochoren\u00ed zistili, \u017ee v CF popul\u00e1cii je n\u00e1sledkom od\u010fa\u013eovania v\u00fdrazne ni\u017e\u0161ia zao\u010dkovanos\u0165 (oproti n\u00e1rodnej sch\u00e9me o\u010dkovania v Gr\u00e9cku). Vo veku 12 mesiacov absolvovalo v\u0161etky potrebn\u00e9 o\u010dkovania 61,4 % det\u00ed s CF a s postupom veku sa toto \u010d\u00edslo \u010falej zni\u017euje, vo veku 12 rokov je to 14,5 %. Autori predpokladaj\u00fa, \u017ee pr\u00ed\u010dinou je, \u017ee po odsunut\u00ed o\u010dkovania sa n\u00e1sledne na\u0148ho nesk\u00f4r neraz \u201czabudne\u201c. Odpor\u00fa\u010daj\u00fa rodi\u010dom a lek\u00e1rom sp\u00e4tne skontrolova\u0165 absolvovanie odpor\u00fa\u010dan\u00fdch o\u010dkovan\u00ed, najm\u00e4 t\u00fdch, ktor\u00e9 boli kv\u00f4li zdravotn\u00fdm komplik\u00e1ci\u00e1m odkladan\u00e9.<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"

Vo Viedni sa koncom apr\u00edla konala v\u00fdznamn\u00e1 infektologick\u00e1 konferencia European Congress of Clinical Microbiology and Infectious Disesases…<\/p>\n","protected":false},"author":7,"featured_media":1940,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"kt_blocks_editor_width":"","footnotes":""},"categories":[253],"tags":[],"class_list":["post-1938","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-o-cystickej-fibroze"],"yoast_head":"\nNovinky z v\u00fdskumu cystickej fibr\u00f3zy na ECCMID 2017 - Slan\u00e9 deti<\/title>\n<meta name=\"description\" content=\"V poslednom obdob\u00ed bola u pacientov s cystickou fibr\u00f3zou op\u00edsan\u00e1 koloniz\u00e1cia nov\u00fdmi druhmi bakt\u00e9ri\u00ed.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/slanedeti.sk\/cms\/novinky-z-vyskumu-cystickej-fibrozy-na-eccmid-2017\/1938\" \/>\n<meta property=\"og:locale\" content=\"sk_SK\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Novinky z v\u00fdskumu cystickej fibr\u00f3zy na ECCMID 2017 - Slan\u00e9 deti\" \/>\n<meta property=\"og:description\" content=\"V poslednom obdob\u00ed bola u pacientov s cystickou fibr\u00f3zou op\u00edsan\u00e1 koloniz\u00e1cia nov\u00fdmi druhmi bakt\u00e9ri\u00ed.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/slanedeti.sk\/cms\/novinky-z-vyskumu-cystickej-fibrozy-na-eccmid-2017\/1938\" \/>\n<meta property=\"og:site_name\" content=\"Slan\u00e9 deti\" \/>\n<meta property=\"article:publisher\" content=\"http:\/\/www.facebook.com\/slanedeti\" \/>\n<meta property=\"article:published_time\" content=\"2017-05-14T15:08:39+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2017-09-03T11:53:12+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/slanedeti.sk\/cms\/wp-content\/uploads\/2017\/05\/ECCMID_2017.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"270\" \/>\n\t<meta property=\"og:image:height\" content=\"270\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"Gallagher\" \/>\n<meta name=\"twitter:label1\" content=\"Autor\" \/>\n\t<meta name=\"twitter:data1\" content=\"Gallagher\" \/>\n\t<meta name=\"twitter:label2\" content=\"Predpokladan\u00fd \u010das \u010d\u00edtania\" \/>\n\t<meta name=\"twitter:data2\" content=\"5 min\u00fat\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/slanedeti.sk\\\/cms\\\/novinky-z-vyskumu-cystickej-fibrozy-na-eccmid-2017\\\/1938#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/slanedeti.sk\\\/cms\\\/novinky-z-vyskumu-cystickej-fibrozy-na-eccmid-2017\\\/1938\"},\"author\":{\"name\":\"Gallagher\",\"@id\":\"https:\\\/\\\/slanedeti.sk\\\/cms\\\/#\\\/schema\\\/person\\\/05d1c3faf9ab837ae66dc01f490cedaa\"},\"headline\":\"Novinky z v\u00fdskumu cystickej fibr\u00f3zy na ECCMID 2017\",\"datePublished\":\"2017-05-14T15:08:39+00:00\",\"dateModified\":\"2017-09-03T11:53:12+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/slanedeti.sk\\\/cms\\\/novinky-z-vyskumu-cystickej-fibrozy-na-eccmid-2017\\\/1938\"},\"wordCount\":1079,\"image\":{\"@id\":\"https:\\\/\\\/slanedeti.sk\\\/cms\\\/novinky-z-vyskumu-cystickej-fibrozy-na-eccmid-2017\\\/1938#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/slanedeti.sk\\\/cms\\\/wp-content\\\/uploads\\\/2017\\\/05\\\/ECCMID_2017.jpg\",\"articleSection\":[\"O cystickej fibr\u00f3ze\"],\"inLanguage\":\"sk-SK\"},{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/slanedeti.sk\\\/cms\\\/novinky-z-vyskumu-cystickej-fibrozy-na-eccmid-2017\\\/1938\",\"url\":\"https:\\\/\\\/slanedeti.sk\\\/cms\\\/novinky-z-vyskumu-cystickej-fibrozy-na-eccmid-2017\\\/1938\",\"name\":\"Novinky z v\u00fdskumu cystickej fibr\u00f3zy na ECCMID 2017 - Slan\u00e9 deti\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/slanedeti.sk\\\/cms\\\/#website\"},\"primaryImageOfPage\":{\"@id\":\"https:\\\/\\\/slanedeti.sk\\\/cms\\\/novinky-z-vyskumu-cystickej-fibrozy-na-eccmid-2017\\\/1938#primaryimage\"},\"image\":{\"@id\":\"https:\\\/\\\/slanedeti.sk\\\/cms\\\/novinky-z-vyskumu-cystickej-fibrozy-na-eccmid-2017\\\/1938#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/slanedeti.sk\\\/cms\\\/wp-content\\\/uploads\\\/2017\\\/05\\\/ECCMID_2017.jpg\",\"datePublished\":\"2017-05-14T15:08:39+00:00\",\"dateModified\":\"2017-09-03T11:53:12+00:00\",\"author\":{\"@id\":\"https:\\\/\\\/slanedeti.sk\\\/cms\\\/#\\\/schema\\\/person\\\/05d1c3faf9ab837ae66dc01f490cedaa\"},\"description\":\"V poslednom obdob\u00ed bola u pacientov s cystickou fibr\u00f3zou op\u00edsan\u00e1 koloniz\u00e1cia nov\u00fdmi druhmi bakt\u00e9ri\u00ed.\",\"inLanguage\":\"sk-SK\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\\\/\\\/slanedeti.sk\\\/cms\\\/novinky-z-vyskumu-cystickej-fibrozy-na-eccmid-2017\\\/1938\"]}]},{\"@type\":\"ImageObject\",\"inLanguage\":\"sk-SK\",\"@id\":\"https:\\\/\\\/slanedeti.sk\\\/cms\\\/novinky-z-vyskumu-cystickej-fibrozy-na-eccmid-2017\\\/1938#primaryimage\",\"url\":\"https:\\\/\\\/slanedeti.sk\\\/cms\\\/wp-content\\\/uploads\\\/2017\\\/05\\\/ECCMID_2017.jpg\",\"contentUrl\":\"https:\\\/\\\/slanedeti.sk\\\/cms\\\/wp-content\\\/uploads\\\/2017\\\/05\\\/ECCMID_2017.jpg\",\"width\":270,\"height\":270,\"caption\":\"ECCMID_2017\"},{\"@type\":\"WebSite\",\"@id\":\"https:\\\/\\\/slanedeti.sk\\\/cms\\\/#website\",\"url\":\"https:\\\/\\\/slanedeti.sk\\\/cms\\\/\",\"name\":\"Slan\u00e9 deti\",\"description\":\"Inform\u00e1cie o cystickej fibr\u00f3ze\",\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\\\/\\\/slanedeti.sk\\\/cms\\\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"sk-SK\"},{\"@type\":\"Person\",\"@id\":\"https:\\\/\\\/slanedeti.sk\\\/cms\\\/#\\\/schema\\\/person\\\/05d1c3faf9ab837ae66dc01f490cedaa\",\"name\":\"Gallagher\",\"url\":\"https:\\\/\\\/slanedeti.sk\\\/cms\\\/author\\\/gallagher\"}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Novinky z v\u00fdskumu cystickej fibr\u00f3zy na ECCMID 2017 - Slan\u00e9 deti","description":"V poslednom obdob\u00ed bola u pacientov s cystickou fibr\u00f3zou op\u00edsan\u00e1 koloniz\u00e1cia nov\u00fdmi druhmi bakt\u00e9ri\u00ed.","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/slanedeti.sk\/cms\/novinky-z-vyskumu-cystickej-fibrozy-na-eccmid-2017\/1938","og_locale":"sk_SK","og_type":"article","og_title":"Novinky z v\u00fdskumu cystickej fibr\u00f3zy na ECCMID 2017 - Slan\u00e9 deti","og_description":"V poslednom obdob\u00ed bola u pacientov s cystickou fibr\u00f3zou op\u00edsan\u00e1 koloniz\u00e1cia nov\u00fdmi druhmi bakt\u00e9ri\u00ed.","og_url":"https:\/\/slanedeti.sk\/cms\/novinky-z-vyskumu-cystickej-fibrozy-na-eccmid-2017\/1938","og_site_name":"Slan\u00e9 deti","article_publisher":"http:\/\/www.facebook.com\/slanedeti","article_published_time":"2017-05-14T15:08:39+00:00","article_modified_time":"2017-09-03T11:53:12+00:00","og_image":[{"width":270,"height":270,"url":"https:\/\/slanedeti.sk\/cms\/wp-content\/uploads\/2017\/05\/ECCMID_2017.jpg","type":"image\/jpeg"}],"author":"Gallagher","twitter_misc":{"Autor":"Gallagher","Predpokladan\u00fd \u010das \u010d\u00edtania":"5 min\u00fat"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"Article","@id":"https:\/\/slanedeti.sk\/cms\/novinky-z-vyskumu-cystickej-fibrozy-na-eccmid-2017\/1938#article","isPartOf":{"@id":"https:\/\/slanedeti.sk\/cms\/novinky-z-vyskumu-cystickej-fibrozy-na-eccmid-2017\/1938"},"author":{"name":"Gallagher","@id":"https:\/\/slanedeti.sk\/cms\/#\/schema\/person\/05d1c3faf9ab837ae66dc01f490cedaa"},"headline":"Novinky z v\u00fdskumu cystickej fibr\u00f3zy na ECCMID 2017","datePublished":"2017-05-14T15:08:39+00:00","dateModified":"2017-09-03T11:53:12+00:00","mainEntityOfPage":{"@id":"https:\/\/slanedeti.sk\/cms\/novinky-z-vyskumu-cystickej-fibrozy-na-eccmid-2017\/1938"},"wordCount":1079,"image":{"@id":"https:\/\/slanedeti.sk\/cms\/novinky-z-vyskumu-cystickej-fibrozy-na-eccmid-2017\/1938#primaryimage"},"thumbnailUrl":"https:\/\/slanedeti.sk\/cms\/wp-content\/uploads\/2017\/05\/ECCMID_2017.jpg","articleSection":["O cystickej fibr\u00f3ze"],"inLanguage":"sk-SK"},{"@type":"WebPage","@id":"https:\/\/slanedeti.sk\/cms\/novinky-z-vyskumu-cystickej-fibrozy-na-eccmid-2017\/1938","url":"https:\/\/slanedeti.sk\/cms\/novinky-z-vyskumu-cystickej-fibrozy-na-eccmid-2017\/1938","name":"Novinky z v\u00fdskumu cystickej fibr\u00f3zy na ECCMID 2017 - Slan\u00e9 deti","isPartOf":{"@id":"https:\/\/slanedeti.sk\/cms\/#website"},"primaryImageOfPage":{"@id":"https:\/\/slanedeti.sk\/cms\/novinky-z-vyskumu-cystickej-fibrozy-na-eccmid-2017\/1938#primaryimage"},"image":{"@id":"https:\/\/slanedeti.sk\/cms\/novinky-z-vyskumu-cystickej-fibrozy-na-eccmid-2017\/1938#primaryimage"},"thumbnailUrl":"https:\/\/slanedeti.sk\/cms\/wp-content\/uploads\/2017\/05\/ECCMID_2017.jpg","datePublished":"2017-05-14T15:08:39+00:00","dateModified":"2017-09-03T11:53:12+00:00","author":{"@id":"https:\/\/slanedeti.sk\/cms\/#\/schema\/person\/05d1c3faf9ab837ae66dc01f490cedaa"},"description":"V poslednom obdob\u00ed bola u pacientov s cystickou fibr\u00f3zou op\u00edsan\u00e1 koloniz\u00e1cia nov\u00fdmi druhmi bakt\u00e9ri\u00ed.","inLanguage":"sk-SK","potentialAction":[{"@type":"ReadAction","target":["https:\/\/slanedeti.sk\/cms\/novinky-z-vyskumu-cystickej-fibrozy-na-eccmid-2017\/1938"]}]},{"@type":"ImageObject","inLanguage":"sk-SK","@id":"https:\/\/slanedeti.sk\/cms\/novinky-z-vyskumu-cystickej-fibrozy-na-eccmid-2017\/1938#primaryimage","url":"https:\/\/slanedeti.sk\/cms\/wp-content\/uploads\/2017\/05\/ECCMID_2017.jpg","contentUrl":"https:\/\/slanedeti.sk\/cms\/wp-content\/uploads\/2017\/05\/ECCMID_2017.jpg","width":270,"height":270,"caption":"ECCMID_2017"},{"@type":"WebSite","@id":"https:\/\/slanedeti.sk\/cms\/#website","url":"https:\/\/slanedeti.sk\/cms\/","name":"Slan\u00e9 deti","description":"Inform\u00e1cie o cystickej fibr\u00f3ze","potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/slanedeti.sk\/cms\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"sk-SK"},{"@type":"Person","@id":"https:\/\/slanedeti.sk\/cms\/#\/schema\/person\/05d1c3faf9ab837ae66dc01f490cedaa","name":"Gallagher","url":"https:\/\/slanedeti.sk\/cms\/author\/gallagher"}]}},"_links":{"self":[{"href":"https:\/\/slanedeti.sk\/cms\/wp-json\/wp\/v2\/posts\/1938","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/slanedeti.sk\/cms\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/slanedeti.sk\/cms\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/slanedeti.sk\/cms\/wp-json\/wp\/v2\/users\/7"}],"replies":[{"embeddable":true,"href":"https:\/\/slanedeti.sk\/cms\/wp-json\/wp\/v2\/comments?post=1938"}],"version-history":[{"count":0,"href":"https:\/\/slanedeti.sk\/cms\/wp-json\/wp\/v2\/posts\/1938\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/slanedeti.sk\/cms\/wp-json\/wp\/v2\/media\/1940"}],"wp:attachment":[{"href":"https:\/\/slanedeti.sk\/cms\/wp-json\/wp\/v2\/media?parent=1938"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/slanedeti.sk\/cms\/wp-json\/wp\/v2\/categories?post=1938"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/slanedeti.sk\/cms\/wp-json\/wp\/v2\/tags?post=1938"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}